New links between vesicle coats and Rab-mediated vesicle targeting
نویسندگان
چکیده
منابع مشابه
New links between vesicle coats and Rab-mediated vesicle targeting.
Vesicle trafficking is a highly regulated process that transports proteins and other cargoes through eukaryotic cells while maintaining cellular organization and compartmental identity. In order for cargo to reach the correct destination, each step of trafficking must impart specificity. During vesicle formation, this is achieved by coat proteins, which selectively incorporate cargo into the na...
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COPI and COPII are vesicle coat complexes whose assembly is regulated by the ARF1 and Sarl GTPases, respectively. We show that COPI and COPII coat complexes are recruited separately and independently to E R (COPII), pre-Golgi (COPI, COPII), and Golgi (COPI) membranes of mammalian cells. To address their individual roles in E R to Golgi transport, we used stage specific in vitro transport assays...
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COPI and COPII are vesicle coat complexes whose assembly is regulated by the ARF1 and Sar1 GTPases, respectively. We show that COPI and COPII coat complexes are recruited separately and independently to ER (COPII), pre-Golgi (COPI, COPII), and Golgi (COPI) membranes of mammalian cells. To address their individual roles in ER to Golgi transport, we used stage specific in vitro transport assays t...
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ژورنال
عنوان ژورنال: Seminars in Cell & Developmental Biology
سال: 2011
ISSN: 1084-9521
DOI: 10.1016/j.semcdb.2010.07.003